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美国眼科学会AAO 简讯         ★★★
美国眼科学会AAO 简讯
作者:佚名 文章来源:网络 点击数:860 更新时间:2015/12/14 22:31:14
This email is a service offered to you by the American Academy of Ophthalmology. 11 December 2015
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NEW JOURNAL STUDIES NEW JOURNAL STUDIES FROM JAPAN (JOS) NEW JOURNAL STUDIES FROM AUSTRALIA AND NEW ZEALAND (RANZCO) ACADEMY NEWS

NEW JOURNAL STUDIES

Treat-and-extend comparable to monthly dosing
Investigators randomized 60 patients with treatment naïve AMD to treat-and-extend (TREX) dosing or fixed monthly dosing with ranibizumab for 1 year. At 12 months, improvements in BCVA and central retinal thickness were similar between groups, but the monthly group had significantly more injections; 13 compared to 10.1 (range, 7 to 13) (P<0.0001). The mean maximum extension interval between injections after the first 3 monthly doses was 8.4 weeks (range, 4 to 12 weeks). Only 22% of TREX patients required monthly dosing, while 37% could extend treatment to 9-week intervals or longer at month 12. Ophthalmology, December 2015

More evidence linking dry eye and depression
Using validated questionnaires, investigators assessed symptoms of dry eye disease (DED) and depression in 53 patients with DED and controls. The association between symptoms of depression and dry eye was linear. DED patients were almost 3 times more likely to have a diagnosis of depression. Depression exacerbated DED symptoms and lead to higher DED symptom scores. However, the mechanisms that underlie the association are unclear. Does DED and its symptoms cause depression through chronic pain or does depression and its medication cause DED? Cornea, December 2015

AS-OCT better predicts angle closure
Investigators assessed the incidence of gonioscopic angle closure after 4 years in 277 patients with baseline open angles on gonioscopy but with angle closure (1-4 quadrants) on anterior segment optical coherence tomography (AS OCT), compared with controls who had baseline open angles on gonioscopy and on AS OCT. Among the study group, 17.3% developed gonioscopic angle closure in 2 or more quadrants and 10.1% developed gonioscopic angle closure in 3 or more quadrants, while none of the controls developed gonioscopic angle closure. Additionally, patients with more quadrants of angle closure at baseline were more likely to develop gonioscopic angle closure after 4 years (P < 0.0001). The authors suggest AS OCT is more sensitive, less prone to artifacts and arguably a less subjective method of detecting iridotrabecular contact and angle-closure glaucoma. Ophthalmology, December 2015

Retinal hemorrhage in children unrelated to vaccinations

This retrospective study evaluated the prevalence and cause of retinal hemorrhage in 5,177 children seen at a single clinic in Philadelphia. The authors found that 9 children (0.17%) developed retinal hemorrhage, all of whom were diagnosed with abusive head trauma from nonocular findings. Among 2,210 children with immunization records, only 1 developed retinal detachment in the 21 days following vaccinations. The authors suggest considering child abuse as the cause of incidental retinal hemorrhage in children. JAMA Ophthalmology, November 2015

Femtosecond-assisted cataract surgery may reduce phaco time in dense cataracts
This prospective study included 240 eyes divided into 4 groups to compare surgery time across cataract grades and between standard and femtosecond-assisted cataract surgery. Laser pretreatment significantly reduced the mean effective phacoemulsification time (EPT) in grade 5 cataracts (P<0.001). Additionally, the EPT for a femtosecond laser–treated grade 5 cataract was most similar to that of a standard-treated grade 3 cataract. The authors conclude that laser pretreatment may reduce complications, such as inflammation and prolonged healing time, in patients with dense cataract. Journal of Cataract & Refractive Surgery, September 2015

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NEW JOURNAL STUDIES FROM JAPAN (JOS)


Retinal pigment epithelial detachment linked to RPE thinning
Investigators evaluated 8 unusual cases of retinal pigment epithelial detachment (PED) with a comorbidity of thinning or nonexistent retinal pigment epithelium (RPE). OCT imaging showed that detachment and thinning corresponded with well-delineated grayish-white lesions at the choroid level through a hypo- or unpigmented area. Hyperfluorescence was detected in these lesions from fluorescein and indocyanine green angiograms, as well as on fundus autofluorescence. The authors suggest that these lesions are possibly a result of focal damage due to longstanding PEDs and may lead to unexpected complications long term. Japanese Journal of Ophthalmology, July 2015

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NEWS FROM AUSTRALIA AND NEW ZEALAND (RANZCO)

IOP spike common after cyclophotocoagulation
This prospective study evaluated the risks associated with IOP spikes following diode laser cyclophotocoagulation. Subjects included in 41 patients (53 eyes) evaluated immediately postop, as well as on days 1, 7, and 90. IOP spikes were common within the first 3 hours: 34% had an increase of ≥3 mm Hg and 18% had an increase ≥10 mm Hg. They authors identified no preoperative or perioperative risk factors and no effect on visual acuity, reduction of glaucoma medication or final postop IOP at 3 months. Still, the authors suggest that a post-laser IOP check is beneficial to detect any significant spikes that may require treatment. Clinical and Experimental Ophthalmology, December 2015

Systemic hydration status broadly affects a variety of ophthalmic conditions
This literature review evaluated the influence of hydration status on ocular physiology and morphological characteristics. The authors found ocular diseases were associated with both dehydration (dry eye syndrome, cataract, refractive changes and retinal vascular disease) and excessive hydration (cataract) and hydration status can be estimated using tear fluid osmolarity. They also found that ocular measurements such as central corneal thickness, IOP, axial length and anterior chamber depth can be effected by a patients’ fluid status. The authors suggest that physicians should briefly assess patients’ hydration status prior to interpreting ocular measurements. Clinical and Experimental Ophthalmology, November 2015

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ACADEMY NEWS

AAO Meetings on Demand
Miss a presentation in Las Vegas? AAO Meetings on Demand captured more than 160 hours of content from AAO 2015 and the Subspecialty Day meetings. View videos from the 6 Subspecialty Day meetings as well as highlights from AAO 2015 on your desktop or mobile device. AAO Meetings on Demand does not offer CME credit.

Latest on macular hole management
This month’s Focal Points discusses new imaging tools that improve diagnosis and management of macular holes. Additionally, advances in therapeutic strategies are reviewed, including the availability of pharmacologic vitreolysis. Learn more by visiting the Academy store.

WOC2016: Learn, participate, connect in Guadalajara, Mexico
Join ophthalmologists from over 100 countries and learn from more than 200 scientific sessions, 1,446 free papers and posters, and 26 Subspecialty Day sessions at the World Ophthalmology Congress® (WOC) of the International Council of Ophthalmology. Seventy ophthalmologic societies have contributed to the scientific program. Connect with old friends and make new ones at social events such as the Mexican Fiesta and Mariachi Gala. Be sure to explore Guadalajara’s historic architecture, fine crafts, excellent cuisine, temperate climate and fun attractions. Register online and save. Online registration closes on Jan. 10. Find more information online.

Great deal: HD camera for surgical microscope
The Academy Foundation is selling a new Ikegami MKC 210HD camera for just $2,000. Ideal for cataract or anterior segment surgery, the unit features an ultra-compact camera head and 1920 x 1080P resolution. Compatible with most Zeiss, Leica, Alcon and Haag-Streit surgical microscopes. This camera usually retails for more than $5,000. It will be sold on a first-come basis with confirmation of payment. Proceeds from the sale will support the Academy’s educational programs. Contact Karen Duke at kduke@aao.org or 415.447.0356 to learn more.

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ASIA PACIFIC ADVISORY PANEL:

Asia Pacific Academy of Ophthalmology (APAO): Dr. Raj V. Azad
Royal Australian and New Zealand College of Ophthalmologists (RANZCO): Drs. Heather Mack and Ralph Higgins
Cambodian Ophthalmological Society (COS):
Drs. Ngy Meng and Mar Amarin
Chinese Ophthalmological Society (COS):
Dr. Xiaoxin Li
All India Ophthalmological Society (AIOS): Drs. S. Natarajan and D. Ramamurthy
Indonesian Ophthalmologist Association (PERDAMI): Drs. Ari Djatikusumo and Tjahjono D. Gondhowiardjo
Japanese Ophthalmological Society (JOS): Dr. Takeshi Yoshitomi, MD, PhD
Korean Ophthalmological Society (KOS): Drs. Young Joon Jo and Min Ahn
Malaysian Society of Ophthalmology (MSO): Dr. Tara Mary George
Mongolian Ophthalmological Society (MOS): Drs. Chimgee Chuluunkhuu and Batchimeg Battumur
Nepal Netra Jyoti Sangh (NNJS): Dr. Ram Prasad Pokhrel
Pacific Eye Care Society (PacEYES): Drs. Rabebe Tekeraoi and Mundi Qalo
Philippine Academy of Ophthalmology (PAO):
Drs. Harvey Uy and Franz Marie Cruz
College of Ophthalmologists of Sri Lanka (CSOL): Drs. Deepanee Wewalwalwala and Manel Pasqual
Ophthalmological Society of Taiwan (TOS): Drs. Ching-Yao Tsai and Po-Ting Yeh
Taiwanese Society of Cataract and Refractive Surgeons (TSCRS): Drs. Tetsaw Chen and David Chaokai Chang
Royal College of Ophthalmologists of Thailand (RCOPT): Drs. Pornchai Simaro, Yosanan Yospaiboon

Editor-in-Chief: Dr. David W. Parke II
Chief Medical Editor: Dr. Philip R. Rizzuto
Managing Editor: Susanne Medeiros

AAO Advisory Panel: Drs. Terry L. Forrest, Jean E. Ramsey, Milam A. Brantley, James C. Tsai, Sunita Radhakrishnan

CONTACT INFORMATION
Asia Pacific Academy of Ophthalmology (APAO): secretariat@APAOphth.org
Royal Australian and New Zealand College of Ophthalmologists (RANZCO): ranzco@ranzco.edu
Cambodian Ophthalmological Society (COS: doseiha@gmail.com
Chinese Ophthalmological Society (COS): cenbj@public3.bta.net.cn
All India Ophthalmological Society (AIOS): secretary@aios.org
Indonesian Ophthalmologist Association (PERDAMI): perdami@indo.net.id
Japanese Ophthalmological Society (JOS): jos2@po.nichigan.or.jp
Korean Ophthalmological Society (KOS): kos@ophthalmology.org
Malaysian Society of Ophthalmology (MSO): msophth@gmail.com
Mongolian Ophthalmological Society (MOS): info@mon-ophth.mn
Nepal Netra Jyoti Sangh (NNJS): kath@nnjs.wlink.com.np
Pacific Eye Care Society (PacEYES): peifiji@gmail.com
Philippine Academy of Ophthalmology (PAO): secretariat_pao@globelines.com.ph
College of Ophthalmologists of Sri Lanka (CSOL): ophsleye@gmail.com
Ophthalmological Society of Taiwan (TOS): oph4@oph.org.tw
Taiwanese Society of Cataract and Refractive Surgeons (TSCRS): mail@tscrs.org.tw
Royal College of Ophthalmologists of Thailand (RCOPT): admin@rcopt.org


The Academy provides the items appearing in the Academy Express as a service to AAO, AIOS, COS, CSOL, JOS, MOS, MSO, NNJS, PAO, PERDAMI, RANZCO, RCOPT, TOS and TSCRS members. The articles and studies come from news reports and peer-reviewed journals, and are not the product, opinion or position of the Academy unless explicitly stated to be so. The Academy does not endorse products, companies or organizations. The Academy disclaims all liability. If you would like to update your email address, ask a question or be removed from the mailing list, send a request to the Academy.

©2015 American Academy of Ophthalmology. All rights reserved.


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